I do not truly understand the Roche biochemical pathways poster.
Preoteomics, genomics, phenomics, connectomics. On the understanding and inference of networks of control in living systems using statistics. Generates lots of interesting problems at the nexus of various other statistical problems, like model selection, false discovery rates, causal graphs and so on.
Of course, there is a deep learning angle.
Is nilearn any good?
References
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Gao, Chuan, Ian C. McDowell, Shiwen Zhao, Christopher D. Brown, and Barbara E. Engelhardt. 2016. โContext Specific and Differential Gene Co-Expression Networks via Bayesian Biclustering.โ PLOS Comput Biol 12 (7): e1004791.
Lahiri, Subhaneil, Peiran Gao, and Surya Ganguli. 2016. โRandom Projections of Random Manifolds.โ arXiv:1607.04331 [Cs, q-Bio, Stat], July.
Perkel, Jeffrey M. 2022. โA Graphics Toolkit for Visualizing Genome Data.โ Nature 608 (7923): 636โ37.
Shen, Yanning, Brian Baingana, and Georgios B. Giannakis. 2016. โNonlinear Structural Vector Autoregressive Models for Inferring Effective Brain Network Connectivity.โ arXiv:1610.06551 [Stat], October.
Srivastava, Sudeep, and Liang Chen. 2010. โA Two-Parameter Generalized Poisson Model to Improve the Analysis of RNA-Seq Data.โ Nucleic Acids Research 38 (17): e170โ70.
Thanei, Gian-Andrea, Nicolai Meinshausen Shah Rajen D., and Rajen D. Shah. 2016. โThe Xyz Algorithm for Fast Interaction Search in High-Dimensional Data.โ Arxiv 20 (9): 846โ51.
Torres, Susana Vรกzquez, Philip J. Y. Leung, Isaac D. Lutz, Preetham Venkatesh, Joseph L. Watson, Fabian Hink, Huu-Hien Huynh, et al. 2022. โDe Novo Design of High-Affinity Protein Binders to Bioactive Helical Peptides.โ bioRxiv.
Watson, Joseph L., David Juergens, Nathaniel R. Bennett, Brian L. Trippe, Jason Yim, Helen E. Eisenach, Woody Ahern, et al. 2022. โBroadly Applicable and Accurate Protein Design by Integrating Structure Prediction Networks and Diffusion Generative Models.โ bioRxiv.
Yao, Shun, Xianyang Zhang, and Xiaofeng Shao. 2016. โTesting Mutual Independence in High Dimension via Distance Covariance.โ arXiv:1609.09380 [Stat], September.
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